The selective degradation of sirtuins via macroautophagy in the MPP(+) model of Parkinson’s disease is promoted by conserved oxidation sites

The sirtuin (SIRT) protein family has been of major research interest over the last decades because of their involvement in aging, cancer, and cell death. SIRTs have been implicated in gene and metabolic regulation through their capacity to remove acyl groups from lysine residues in proteins in an N...

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Detalles Bibliográficos
Autores principales: Baeken, Marius W., Schwarz, Mario, Kern, Andreas, Moosmann, Bernd, Hajieva, Parvana, Behl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511006/
https://www.ncbi.nlm.nih.gov/pubmed/34642296
http://dx.doi.org/10.1038/s41420-021-00683-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511006/
https://www.ncbi.nlm.nih.gov/pubmed/34642296
http://dx.doi.org/10.1038/s41420-021-00683-x

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