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The selective degradation of sirtuins via macroautophagy in the MPP(+) model of Parkinson’s disease is promoted by conserved oxidation sites
The sirtuin (SIRT) protein family has been of major research interest over the last decades because of their involvement in aging, cancer, and cell death. SIRTs have been implicated in gene and metabolic regulation through their capacity to remove acyl groups from lysine residues in proteins in an N...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511006/ https://www.ncbi.nlm.nih.gov/pubmed/34642296 http://dx.doi.org/10.1038/s41420-021-00683-x |