Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt

Metformin, traditionally regarded as a hypoglycemic drug, has been studied in other various fields including inflammation. The specific mechanism of metformin’s effect on immune cells remains unclear. Herein, it is verified that LPS-induced macrophages are characterized by enhanced endogenous fatty...

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Detalles Bibliográficos
Autores principales: Xiong, Wenfang, Sun, Kuo-Yang, Zhu, Yan, Zhang, Xiaoqi, Zhou, Yi-Hua, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511025/
https://www.ncbi.nlm.nih.gov/pubmed/34642298
http://dx.doi.org/10.1038/s41419-021-04235-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511025/
https://www.ncbi.nlm.nih.gov/pubmed/34642298
http://dx.doi.org/10.1038/s41419-021-04235-0

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