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hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic cells have multiple pathways to efficiently detect, signal and repair DNA damage. One common form of exogenous DNA damage comes from ultraviolet B (UVB) radiation. UVB generates cyclobutane pyrimidin...

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Detalles Bibliográficos
Autores principales: Boucher, Didier, Kariawasam, Ruvini, Burgess, Joshua, Gimenez, Adrian, Ocampo, Tristan E., Ferguson, Blake, Naqi, Ali, Walker, Graeme J., Bolderson, Emma, Gamsjaeger, Roland, O’Byrne, Kenneth J., Cubeddu, Liza, Khanna, Kum Kum, Richard, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511049/
https://www.ncbi.nlm.nih.gov/pubmed/34642383
http://dx.doi.org/10.1038/s41598-021-99355-0