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Disturbance of phylogenetic layer-specific adaptation of human brain gene expression in Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with typical neuropathological hallmarks, such as neuritic plaques and neurofibrillary tangles, preferentially found at layers III and V. The distribution of both hallmarks provides the basis for the staging of AD, following a...

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Detalles Bibliográficos
Autores principales: Jorge, Natasha Andressa Nogueira, Ueberham, Uwe, Knobloch, Mara, Stadler, Peter F., Fallmann, Jörg, Arendt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511061/
https://www.ncbi.nlm.nih.gov/pubmed/34642398
http://dx.doi.org/10.1038/s41598-021-99760-5