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The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma

Glioblastoma (GBM) is a brain malignancy characterized by invasiveness to the surrounding brain tissue and by stem-like cells, which propagate the tumor and may also regulate invasiveness. During brain development, polarity proteins, such as Par3, regulate asymmetric cell division of neuro-glial pro...

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Detalles Bibliográficos
Autores principales: Dadras, Mahsa Shahidi, Caja, Laia, Mezheyeuski, Artur, Liu, Sijia, Gélabert, Caroline, Gomez-Puerto, Maria Catalina, Gallini, Radiosa, Rubin, Carl-Johan, ten Dijke, Peter, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511086/
https://www.ncbi.nlm.nih.gov/pubmed/34642295
http://dx.doi.org/10.1038/s41419-021-04220-7