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The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma
Glioblastoma (GBM) is a brain malignancy characterized by invasiveness to the surrounding brain tissue and by stem-like cells, which propagate the tumor and may also regulate invasiveness. During brain development, polarity proteins, such as Par3, regulate asymmetric cell division of neuro-glial pro...
Autores principales: | Dadras, Mahsa Shahidi, Caja, Laia, Mezheyeuski, Artur, Liu, Sijia, Gélabert, Caroline, Gomez-Puerto, Maria Catalina, Gallini, Radiosa, Rubin, Carl-Johan, ten Dijke, Peter, Heldin, Carl-Henrik, Moustakas, Aristidis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511086/ https://www.ncbi.nlm.nih.gov/pubmed/34642295 http://dx.doi.org/10.1038/s41419-021-04220-7 |
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