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Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis

Systemic sclerosis (SSc) is a chronic multisystem disorder characterized by fibrosis and autoimmunity. Interleukin (IL)-31 has been implicated in fibrosis and T helper (Th) 2 immune responses, both of which are characteristics of SSc. The exact role of IL-31 in SSc pathogenesis is unclear. Here we s...

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Detalles Bibliográficos
Autores principales: Kuzumi, Ai, Yoshizaki, Ayumi, Matsuda, Kazuki M., Kotani, Hirohito, Norimatsu, Yuta, Fukayama, Maiko, Ebata, Satoshi, Fukasawa, Takemichi, Yoshizaki-Ogawa, Asako, Asano, Yoshihide, Morikawa, Kyojiro, Kazoe, Yutaka, Mawatari, Kazuma, Kitamori, Takehiko, Sato, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511151/
https://www.ncbi.nlm.nih.gov/pubmed/34642338
http://dx.doi.org/10.1038/s41467-021-26099-w