Estimation of cell-free fetal DNA fraction from maternal plasma based on linkage disequilibrium information

Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the performance of noninvasive prenatal testing (NIPT). Accurate quantitation of FF plays a pivotal role in these tests. However, there are few methods that could determine FF with high accuracy using shallow‐depth who...

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Detalles Bibliográficos
Autores principales: Ju, Jia, Li, Jia, Liu, Siyang, Zhang, Haiqiang, Xu, Jinjin, Lin, Yu, Gao, Ya, Zhou, Yulin, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511193/
https://www.ncbi.nlm.nih.gov/pubmed/34642337
http://dx.doi.org/10.1038/s41525-021-00247-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511193/
https://www.ncbi.nlm.nih.gov/pubmed/34642337
http://dx.doi.org/10.1038/s41525-021-00247-z

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