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Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

The surface polysacharide arabinomannan (AM) and related glycolipid lipoarabinomannan (LAM) play critical roles in tuberculosis pathogenesis. Human antibody responses to AM/LAM are heterogenous and knowledge of reactivity to specific glycan epitopes at the monoclonal level is limited, especially in...

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Detalles Bibliográficos
Autores principales: Ishida, Elise, Corrigan, Devin T., Malonis, Ryan J., Hofmann, Daniel, Chen, Tingting, Amin, Anita G., Chatterjee, Delphi, Joe, Maju, Lowary, Todd L., Lai, Jonathan R., Achkar, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511196/
https://www.ncbi.nlm.nih.gov/pubmed/34642445
http://dx.doi.org/10.1038/s42003-021-02714-w