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Long-read sequencing reveals the structural complexity of genomic integration of HBV DNA in hepatocellular carcinoma
The integration of HBV DNA into the human genome can disrupt its structure in hepatocellular carcinoma (HCC), but the complexity of HBV genomic integration remains elusive. Here we applied long-read sequencing to precisely elucidate the HBV integration pattern in the human hepatocellular genome. The...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511263/ https://www.ncbi.nlm.nih.gov/pubmed/34642322 http://dx.doi.org/10.1038/s41525-021-00245-1 |