Long-read sequencing reveals the structural complexity of genomic integration of HBV DNA in hepatocellular carcinoma

The integration of HBV DNA into the human genome can disrupt its structure in hepatocellular carcinoma (HCC), but the complexity of HBV genomic integration remains elusive. Here we applied long-read sequencing to precisely elucidate the HBV integration pattern in the human hepatocellular genome. The...

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Detalles Bibliográficos
Autores principales: Zhuo, Zhongling, Rong, Weiqi, Li, Hexin, Li, Ying, Luo, Xuanmei, Liu, Ye, Tang, Xiaokun, Zhang, Lili, Su, Fei, Cui, Hongyuan, Xiao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511263/
https://www.ncbi.nlm.nih.gov/pubmed/34642322
http://dx.doi.org/10.1038/s41525-021-00245-1

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