Eicosanoid Metabolomic Profile of Remdesivir Treatment in Rat Plasma by High-Performance Liquid Chromatography Mass Spectrometry

Remdesivir, a nucleotide analog prodrug, has displayed pharmacological activity against SARS-CoV-2. Recently, eicosanoids are widely involved in regulating immunity and inflammation for COVID-19 patients. Rats were intravenously administered remdesivir at a dose of 5 mg/kg, and series of blood sampl...

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Detalles Bibliográficos
Autores principales: Du, Ping, Wang, Guo-yong, Zhao, Rui, An, Zhuo-ling, Liu, Li-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511316/
https://www.ncbi.nlm.nih.gov/pubmed/34658883
http://dx.doi.org/10.3389/fphar.2021.747450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511316/
https://www.ncbi.nlm.nih.gov/pubmed/34658883
http://dx.doi.org/10.3389/fphar.2021.747450

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