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Eicosanoid Metabolomic Profile of Remdesivir Treatment in Rat Plasma by High-Performance Liquid Chromatography Mass Spectrometry

Remdesivir, a nucleotide analog prodrug, has displayed pharmacological activity against SARS-CoV-2. Recently, eicosanoids are widely involved in regulating immunity and inflammation for COVID-19 patients. Rats were intravenously administered remdesivir at a dose of 5 mg/kg, and series of blood sampl...

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Detalles Bibliográficos
Autores principales:	Du, Ping, Wang, Guo-yong, Zhao, Rui, An, Zhuo-ling, Liu, Li-hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511316/ https://www.ncbi.nlm.nih.gov/pubmed/34658883 http://dx.doi.org/10.3389/fphar.2021.747450

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