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Optimization of Linezolid Dosing Regimens for Treatment of Vancomycin-Resistant Enterococci Infection

BACKGROUND: Linezolid, an oxazolidinone antibiotic, is recommended for vancomycin-resistant enterococci (VRE). However, 100% free-drug concentration above the minimum inhibitory concentration (fT>MIC) and an area under the curve of free drug to MIC ratio (fAUC24/MIC) >100 were associated with...

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Detalles Bibliográficos
Autores principales: Santimaleeworagun, Wichai, Changpradub, Dhitiwat, Hemapanpairoa, Jatapat, Thunyaharn, Sudaluck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy; The Korean Society for AIDS 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511381/
https://www.ncbi.nlm.nih.gov/pubmed/34405596
http://dx.doi.org/10.3947/ic.2021.0034