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TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism

T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) is an immunosuppressive receptor expressed on the surface of immune cells, suppressing immune responses by activating the intracellular negative regulatory signals. TIGIT plays an important role in the pathogenes...

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Detalles Bibliográficos
Autores principales: Shao, Qi, Wang, Lei, Yuan, Maoling, Jin, Xiaohong, Chen, Zhiming, Wu, Changping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511404/
https://www.ncbi.nlm.nih.gov/pubmed/34659197
http://dx.doi.org/10.3389/fimmu.2021.688961