Cargando…
TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism
T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) is an immunosuppressive receptor expressed on the surface of immune cells, suppressing immune responses by activating the intracellular negative regulatory signals. TIGIT plays an important role in the pathogenes...
Autores principales: | Shao, Qi, Wang, Lei, Yuan, Maoling, Jin, Xiaohong, Chen, Zhiming, Wu, Changping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511404/ https://www.ncbi.nlm.nih.gov/pubmed/34659197 http://dx.doi.org/10.3389/fimmu.2021.688961 |
Ejemplares similares
-
TIGIT Blockade Exerts Synergistic Effects on Microwave Ablation Against Cancer
por: Chen, Yaping, et al.
Publicado: (2022) -
CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells
por: Yasutomi, Motoko, et al.
Publicado: (2022) -
Imbalance of the CD226/TIGIT Immune Checkpoint Is Involved in the Pathogenesis of Primary Biliary Cholangitis
por: Deng, Chuiwen, et al.
Publicado: (2020) -
Co-Expression of TIGIT and Helios Marks Immunosenescent CD8(+) T Cells During Aging
por: Pieren, Daan K. J., et al.
Publicado: (2022) -
Analysis of the Characteristics of TIGIT-Expressing CD3(−)CD56(+)NK Cells in Controlling Different Stages of HIV-1 Infection
por: Zhang, Xin, et al.
Publicado: (2021)