Tumor Mutational Burden Predicting the Efficacy of Immune Checkpoint Inhibitors in Colorectal Cancer: A Systematic Review and Meta-Analysis

OBJECTIVES: For colorectal cancer patients, traditional biomarker deficient mismatch repair/microsatellite instability (dMMR/MSI) is an accurate predictor of immune checkpoint inhibitors (ICIs). Recent years, researchers considered tumor mutation burden (TMB) as another predictive biomarker which me...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ma, Yiqi, Wu, Zijun, Zeng, Fanxin, Song, Bin, Zhang, Yanrong, Li, Jinxing, Lui, Su, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511407/
https://www.ncbi.nlm.nih.gov/pubmed/34659255
http://dx.doi.org/10.3389/fimmu.2021.751407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511407/
https://www.ncbi.nlm.nih.gov/pubmed/34659255
http://dx.doi.org/10.3389/fimmu.2021.751407

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