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Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes

Patients undergoing radiotherapy (RT) for various tumors localized in the abdomen or pelvis often suffer from radiation nephrotoxicity as collateral damage. Renal podocytes are vulnerable targets for ionizing radiation and contribute to radiation-induced nephropathies. Our prior work previously high...

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Detalles Bibliográficos
Autores principales: Azzam, Patrick, Francis, Marina, Youssef, Tarek, Mroueh, Manal, Daher, Alaa Abou, Eid, Assaad A., Fornoni, Alessia, Marples, Brian, Zeidan, Youssef H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511442/
https://www.ncbi.nlm.nih.gov/pubmed/34660640
http://dx.doi.org/10.3389/fmed.2021.732528