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Neuroprotective Effects of Ceftriaxone Involve the Reduction of Aβ Burden and Neuroinflammatory Response in a Mouse Model of Alzheimer’s Disease

Ceftriaxone (CEF) is a safe and multipotent antimicrobial agent that possesses neuroprotective properties. Earlier, we revealed the restoration of cognitive function in OXYS rats with signs of Alzheimer’s disease (AD)-like pathology by CEF along with its modulating the expression of genes related to...

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Detalles Bibliográficos
Autores principales: Tikhonova, Maria A., Amstislavskaya, Tamara G., Ho, Ying-Jui, Akopyan, Anna A., Tenditnik, Michael V., Ovsyukova, Marina V., Bashirzade, Alim A., Dubrovina, Nina I., Aftanas, Lyubomir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511453/
https://www.ncbi.nlm.nih.gov/pubmed/34658774
http://dx.doi.org/10.3389/fnins.2021.736786