Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish

In the zebrafish embryo, the onset of blood flow generates fluid shear stress on endocardial cells, which are specialized endothelial cells that line the interior of the heart. High levels of fluid shear stress activate both Notch and Klf2 signaling, which play crucial roles in atrioventricular valv...

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Detalles Bibliográficos
Autores principales: Paolini, Alessio, Fontana, Federica, Pham, Van-Cuong, Rödel, Claudia Jasmin, Abdelilah-Seyfried, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511505/
https://www.ncbi.nlm.nih.gov/pubmed/34610316
http://dx.doi.org/10.1016/j.celrep.2021.109782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511505/
https://www.ncbi.nlm.nih.gov/pubmed/34610316
http://dx.doi.org/10.1016/j.celrep.2021.109782

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