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STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-Δ(12,14)-prostaglandin J(2) in Triple Negative Breast Cancer

STAT3 plays a prominent role in proliferation and survival of tumor cells. Thus, STAT3 has been considered to be a prime target for development of anti-cancer therapeutics. The electrophilic cyclopentenone prostaglandin,15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been well recognized for i...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jung, Cho, Nam-Chul, Hahn, Young-Il, Kim, Seong Hoon, Fang, Xizhu, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511581/
https://www.ncbi.nlm.nih.gov/pubmed/34703823
http://dx.doi.org/10.15430/JCP.2021.26.3.207