Glycolysis Inhibition Alleviates Cardiac Fibrosis After Myocardial Infarction by Suppressing Cardiac Fibroblast Activation

Objective: To explore the role of glycolysis in cardiac fibroblast (CF) activation and cardiac fibrosis after myocardial infarction (MI). Method: In vivo: 2-Deoxy-D-glucose (2-DG), a glycolysis inhibitor, was injected into the abdominal cavity of the MI or sham mice every day. On the 28th day, cardi...

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Detalles Bibliográficos
Autores principales: Chen, Zhi-Teng, Gao, Qing-Yuan, Wu, Mao-Xiong, Wang, Meng, Sun, Run-Lu, Jiang, Yuan, Guo, Qi, Guo, Da-Chuan, Liu, Chi-Yu, Chen, Si-Xu, Liu, Xiao, Wang, Jing-Feng, Zhang, Hai-Feng, Chen, Yang-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511672/
https://www.ncbi.nlm.nih.gov/pubmed/34660710
http://dx.doi.org/10.3389/fcvm.2021.701745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511672/
https://www.ncbi.nlm.nih.gov/pubmed/34660710
http://dx.doi.org/10.3389/fcvm.2021.701745

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