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Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation

Endothelial wingless-related integration site (Wnt)-/β-catenin signaling is a key regulator of the tightly sealed blood–brain barrier. In the hepatic vascular niche angiokine-mediated Wnt signaling was recently identified as an important regulator of hepatocyte function, including the determination...

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Detalles Bibliográficos
Autores principales: Koch, Philipp-Sebastian, Sandorski, Kajetan, Heil, Joschka, Schmid, Christian D., Kürschner, Sina W., Hoffmann, Johannes, Winkler, Manuel, Staniczek, Theresa, de la Torre, Carolina, Sticht, Carsten, Schledzewski, Kai, Taketo, Makoto Mark, Trogisch, Felix A., Heineke, Joerg, Géraud, Cyrill, Goerdt, Sergij, Olsavszky, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511684/
https://www.ncbi.nlm.nih.gov/pubmed/34658910
http://dx.doi.org/10.3389/fphys.2021.722394