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Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation
Endothelial wingless-related integration site (Wnt)-/β-catenin signaling is a key regulator of the tightly sealed blood–brain barrier. In the hepatic vascular niche angiokine-mediated Wnt signaling was recently identified as an important regulator of hepatocyte function, including the determination...
Autores principales: | Koch, Philipp-Sebastian, Sandorski, Kajetan, Heil, Joschka, Schmid, Christian D., Kürschner, Sina W., Hoffmann, Johannes, Winkler, Manuel, Staniczek, Theresa, de la Torre, Carolina, Sticht, Carsten, Schledzewski, Kai, Taketo, Makoto Mark, Trogisch, Felix A., Heineke, Joerg, Géraud, Cyrill, Goerdt, Sergij, Olsavszky, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511684/ https://www.ncbi.nlm.nih.gov/pubmed/34658910 http://dx.doi.org/10.3389/fphys.2021.722394 |
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