Case Report: Immune and Genomic Characteristics Associated With Hyperprogression in a Patient With Metastatic Deficient Mismatch Repair Gastrointestinal Cancer Treated With Anti-PD-1 Antibody

Microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) status of tumors is a distinct predictive biomarker of immune checkpoint inhibitors (ICIs) for colorectal and non-colorectal cancer populations. The overall response rate (ORR) varies from approximately 40% to 60%, indicating tha...

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Detalles Bibliográficos
Autores principales: Zhou, Wenyue, Zhou, Yuwen, Yi, Cheng, Shu, Xinyao, Wei, Guixia, Chen, Xiaorong, Shen, Xudong, Qiu, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511698/
https://www.ncbi.nlm.nih.gov/pubmed/34659249
http://dx.doi.org/10.3389/fimmu.2021.749204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511698/
https://www.ncbi.nlm.nih.gov/pubmed/34659249
http://dx.doi.org/10.3389/fimmu.2021.749204

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