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SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential

BACKGROUND: Metabolic reprogramming plays an essential role on lymphoma progression. Dysregulation of glutamine metabolism is implicated in natural-killer T-cell lymphoma (NKTCL) and tumor cell response to asparaginase-based anti-metabolic treatment. METHODS: To understand the metabolomic alteration...

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Detalles Bibliográficos
Autores principales: Xiong, Jie, Wang, Nan, Zhong, Hui-Juan, Cui, Bo-Wen, Cheng, Shu, Sun, Rui, Chen, Jia-Yi, Xu, Peng-Peng, Cai, Gang, Wang, Li, Sun, Xiao-Jian, Huang, Jin-Yan, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511843/
https://www.ncbi.nlm.nih.gov/pubmed/34628354
http://dx.doi.org/10.1016/j.ebiom.2021.103614