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SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential
BACKGROUND: Metabolic reprogramming plays an essential role on lymphoma progression. Dysregulation of glutamine metabolism is implicated in natural-killer T-cell lymphoma (NKTCL) and tumor cell response to asparaginase-based anti-metabolic treatment. METHODS: To understand the metabolomic alteration...
Autores principales: | Xiong, Jie, Wang, Nan, Zhong, Hui-Juan, Cui, Bo-Wen, Cheng, Shu, Sun, Rui, Chen, Jia-Yi, Xu, Peng-Peng, Cai, Gang, Wang, Li, Sun, Xiao-Jian, Huang, Jin-Yan, Zhao, Wei-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511843/ https://www.ncbi.nlm.nih.gov/pubmed/34628354 http://dx.doi.org/10.1016/j.ebiom.2021.103614 |
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