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Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake

Background: The synthetic steroid mifepristone is reported to have anti-obesity and anti-diabetic effects in mammals on normal and high-fat diets (HFD). We previously reported that mifepristone blocks the negative effect on life span caused by mating in female Drosophila melanogaster. Methods: Here...

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Detalles Bibliográficos
Autores principales: Landis, Gary N., Hilsabeck, Tyler A. U., Bell, Hans S., Ronnen-Oron, Tal, Wang, Lu, Doherty, Devon V., Tejawinata, Felicia I., Erickson, Katherine, Vu, William, Promislow, Daniel E. L., Kapahi, Pankaj, Tower, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511958/
https://www.ncbi.nlm.nih.gov/pubmed/34659367
http://dx.doi.org/10.3389/fgene.2021.751647