Cargando…

Convertible and Constrained Nucleotides: The 2’-Deoxyribose 5’-C-Functionalization Approach, a French Touch

Many strategies have been developed to modulate the biological or biotechnical properties of oligonucleotides by introducing new chemical functionalities or by enhancing their affinity and specificity while restricting their conformational space. Among them, we review our approach consisting of modi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chardet, Crystalle, Payrastre, Corinne, Gerland, Béatrice, Escudier, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512084/
https://www.ncbi.nlm.nih.gov/pubmed/34641475
http://dx.doi.org/10.3390/molecules26195925