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Unambiguous Stereochemical Assignment of Cyclo(Phe-Pro), Cyclo(Leu-Pro), and Cyclo(Val-Pro) by Electronic Circular Dichroic Spectroscopy

2,5-diketopiperazines (DKPs) are cyclic dipeptides ubiquitously found in nature. In particular, cyclo(Phe-Pro), cyclo(Leu-Pro), and cyclo(Val-Pro) are frequently detected in many microbial cultures. Each of these DKPs has four possible stereoisomers due to the presence of two chirality centers. Howe...

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Detalles Bibliográficos
Autores principales: Domzalski, Alison, Margent, Liliana, Vigo, Valeria, Dewan, Faizunnahar, Pilarsetty, Naga Vara Kishore, Xu, Yujia, Kawamura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512403/
https://www.ncbi.nlm.nih.gov/pubmed/34641525
http://dx.doi.org/10.3390/molecules26195981