The Reactions of 6-(Hydroxymethyl)-2,2-dimethyl-1-azaspiro[4.4]nonanes with Methanesulfonyl Chloride or PPh(3)-CBr(4)

Activation of a hydroxyl group towards nucleophilic substitution via reaction with methanesulfonyl chloride or PPh(3)-CBr(4) system is a commonly used pathway to various functional derivatives. The reactions of (5R(S),6R(S))-1-X-6-(hydroxymethyl)-2,2-dimethyl- 1-azaspiro[4.4]nonanes 1a–d (X = O·; H;...

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Detalles Bibliográficos
Autores principales: Khoroshunova, Yulia V., Morozov, Denis A., Taratayko, Andrey I., Dobrynin, Sergey A., Eltsov, Ilia V., Rybalova, Tatyana V., Sotnikova, Yulia S., Polovyanenko, Dmitriy N., Asanbaeva, Nargiz B., Kirilyuk, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512565/
https://www.ncbi.nlm.nih.gov/pubmed/34641544
http://dx.doi.org/10.3390/molecules26196000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512565/
https://www.ncbi.nlm.nih.gov/pubmed/34641544
http://dx.doi.org/10.3390/molecules26196000

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