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The Reactions of 6-(Hydroxymethyl)-2,2-dimethyl-1-azaspiro[4.4]nonanes with Methanesulfonyl Chloride or PPh(3)-CBr(4)
Activation of a hydroxyl group towards nucleophilic substitution via reaction with methanesulfonyl chloride or PPh(3)-CBr(4) system is a commonly used pathway to various functional derivatives. The reactions of (5R(S),6R(S))-1-X-6-(hydroxymethyl)-2,2-dimethyl- 1-azaspiro[4.4]nonanes 1a–d (X = O·; H;...
Autores principales: | Khoroshunova, Yulia V., Morozov, Denis A., Taratayko, Andrey I., Dobrynin, Sergey A., Eltsov, Ilia V., Rybalova, Tatyana V., Sotnikova, Yulia S., Polovyanenko, Dmitriy N., Asanbaeva, Nargiz B., Kirilyuk, Igor A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512565/ https://www.ncbi.nlm.nih.gov/pubmed/34641544 http://dx.doi.org/10.3390/molecules26196000 |
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