Structural Basis for PPARs Activation by The Dual PPARα/γ Agonist Sanguinarine: A Unique Mode of Ligand Recognition

Peroxisome proliferator-activated receptors (PPARs) play crucial roles in glucose and lipid metabolism and inflammation. Sanguinarine is a natural product that is isolated from Sanguinaria Canadensis, a potential therapeutic agent for intervention in chronic diseases. In this study, biochemical and...

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Detalles Bibliográficos
Autores principales: Tian, Siyu, Wang, Rui, Chen, Shuming, He, Jialing, Zheng, Weili, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512631/
https://www.ncbi.nlm.nih.gov/pubmed/34641558
http://dx.doi.org/10.3390/molecules26196012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512631/
https://www.ncbi.nlm.nih.gov/pubmed/34641558
http://dx.doi.org/10.3390/molecules26196012

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