Discovery of Active Ingredients Targeted TREM2 by SPR Biosensor-UPLC/MS Recognition System, and Investigating the Mechanism of Anti-Neuroinflammatory Activity on the Lignin-Amides from Datura metel Seeds

As a new target protein for Alzheimer’s disease (AD), the triggering receptor expressed on myeloid Cells 2 (TREM2) was expressed on the surface of microglia, which was shown to regulate neuroinflammation, be associated with a variety of neuropathologic, and regarded as a potential indicator for moni...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Si-Yi, Liu, Yan, Li, Xiao-Mao, Algradi, Adnan Mohammed, Jiang, Hai, Sun, Yan-Ping, Guan, Wei, Pan, Juan, Kuang, Hai-Xue, Yang, Bing-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512677/
https://www.ncbi.nlm.nih.gov/pubmed/34641490
http://dx.doi.org/10.3390/molecules26195946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512677/
https://www.ncbi.nlm.nih.gov/pubmed/34641490
http://dx.doi.org/10.3390/molecules26195946

Ejemplares similares