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New 4-Aminoproline-Based Small Molecule Cyclopeptidomimetics as Potential Modulators of α(4)β(1) Integrin

Integrin α(4)β(1) belongs to the leukocyte integrin family and represents a therapeutic target of relevant interest given its primary role in mediating inflammation, autoimmune pathologies and cancer-related diseases. The focus of the present work is the design, synthesis and characterization of new...

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Detalles Bibliográficos
Autores principales: Sartori, Andrea, Bugatti, Kelly, Portioli, Elisabetta, Baiula, Monica, Casamassima, Irene, Bruno, Agostino, Bianchini, Francesca, Curti, Claudio, Zanardi, Franca, Battistini, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512764/
https://www.ncbi.nlm.nih.gov/pubmed/34641610
http://dx.doi.org/10.3390/molecules26196066