Synthesis and Pharmacological Evaluation of Novel 2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole Derivatives as Promising Anxiolytic and Analgesic Agents

A number of novel 2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole derivatives 2 were obtained by alkylation mainly in the 1H-tautomeric form of 2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole or its 8,9-dimethyl-substituted analog 4-chlorobenzyl bromide, 4-chloroacetic acid fluoroanilide,...

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Detalles Bibliográficos
Autores principales: Maltsev, Dmitriy V., Spasov, Alexander A., Vassiliev, Pavel M., Skripka, Maria O., Miroshnikov, Mikhail V., Kochetkov, Andrey N., Eliseeva, Nataliya V., Lifanova, Yuliya V., Kuzmenko, Tatyana A., Divaeva, Lyudmila N., Morkovnik, Anatolii S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512782/
https://www.ncbi.nlm.nih.gov/pubmed/34641593
http://dx.doi.org/10.3390/molecules26196049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512782/
https://www.ncbi.nlm.nih.gov/pubmed/34641593
http://dx.doi.org/10.3390/molecules26196049

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