Synthesis of Indoloquinolines: An Intramolecular Cyclization Leading to Advanced Perophoramidine-Relevant Intermediates

The bioactive natural product perophoramidine has proved a challenging synthetic target. An alternative route to its indolo[2,3-b]quinolone core structure involving a N-chlorosuccinimde-mediated intramolecular cyclization reaction is reported. Attempts to progress towards the natural product are als...

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Detalles Bibliográficos
Autores principales: Johnston, Craig A., Cordes, David B., Lebl, Tomas, Slawin, Alexandra M. Z., Westwood, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513048/
https://www.ncbi.nlm.nih.gov/pubmed/34641583
http://dx.doi.org/10.3390/molecules26196039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513048/
https://www.ncbi.nlm.nih.gov/pubmed/34641583
http://dx.doi.org/10.3390/molecules26196039

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