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Glyceric Prodrug of Ursodeoxycholic Acid (UDCA): Novozym 435-Catalyzed Synthesis of UDCA-Monoglyceride

Bile acids (BAs) are a family of steroids synthesized from cholesterol in the liver. Among bile acids, ursodeoxycholic acid (UDCA) is the drug of choice for treating primary biliary cirrhosis and dissolving cholesterol gallstones. The clinical effectiveness of UDCA includes its choleretic activity,...

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Detalles Bibliográficos
Autores principales: Zappaterra, Federico, Costa, Stefania, Summa, Daniela, Semeraro, Bruno, Cristofori, Virginia, Trapella, Claudio, Tamburini, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513054/
https://www.ncbi.nlm.nih.gov/pubmed/34641510
http://dx.doi.org/10.3390/molecules26195966