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Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street
BACKGROUND: A strong association of obesity and insulin resistance with increased circulating levels of branched-chain and aromatic amino acids and decreased glycine levels has been recognized in human subjects for decades. SCOPE OF REVIEW: More recently, human metabolomics and genetic studies have...
Autores principales: | White, Phillip J., McGarrah, Robert W., Herman, Mark A., Bain, James R., Shah, Svati H., Newgard, Christopher B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513145/ https://www.ncbi.nlm.nih.gov/pubmed/34044180 http://dx.doi.org/10.1016/j.molmet.2021.101261 |
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