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Understanding insulin and its receptor from their three-dimensional structures
BACKGROUND: Insulin's discovery 100 years ago and its ongoing use since that time to treat diabetes belies the molecular complexity of its structure and that of its receptor. Advances in single-particle cryo-electron microscopy have over the past three years revolutionized our understanding of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513149/ https://www.ncbi.nlm.nih.gov/pubmed/33992784 http://dx.doi.org/10.1016/j.molmet.2021.101255 |