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Understanding insulin and its receptor from their three-dimensional structures

BACKGROUND: Insulin's discovery 100 years ago and its ongoing use since that time to treat diabetes belies the molecular complexity of its structure and that of its receptor. Advances in single-particle cryo-electron microscopy have over the past three years revolutionized our understanding of...

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Detalles Bibliográficos
Autor principal: Lawrence, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513149/
https://www.ncbi.nlm.nih.gov/pubmed/33992784
http://dx.doi.org/10.1016/j.molmet.2021.101255