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Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes

BACKGROUND: Insulin has been demonstrated to exert direct and indirect effects on vascular tissues. Its actions in vascular cells are mediated by two major pathways: the insulin receptor substrate 1/2-phosphoinositide-3 kinase/Akt (IRS1/2/PI3K/Akt) pathway and the Src/mitogen-activated protein kinas...

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Detalles Bibliográficos
Autores principales: Fu, Jialin, Yu, Marc Gregory, Li, Qian, Park, Kyoungmin, King, George L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513152/
https://www.ncbi.nlm.nih.gov/pubmed/33878400
http://dx.doi.org/10.1016/j.molmet.2021.101236