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Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes
BACKGROUND: Insulin has been demonstrated to exert direct and indirect effects on vascular tissues. Its actions in vascular cells are mediated by two major pathways: the insulin receptor substrate 1/2-phosphoinositide-3 kinase/Akt (IRS1/2/PI3K/Akt) pathway and the Src/mitogen-activated protein kinas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513152/ https://www.ncbi.nlm.nih.gov/pubmed/33878400 http://dx.doi.org/10.1016/j.molmet.2021.101236 |