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Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway

BACKGROUND: Trophoblast dysfunction during pregnancy is fundamentally involved in preeclampsia. Several studies have revealed that human chorionic villous mesenchymal stem cells (CV-MSCs) could regulate trophoblasts function. RESULTS: To understand how human chorionic villous mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Chu, Yijing, Zhu, Chengzhan, Yue, Chongyu, Peng, Wei, Chen, Weiping, He, Guifang, Liu, Changchang, Lv, Yang, Gao, Guoqiang, Yao, Ke, Han, Rendong, Hu, Xiaoyu, Zhang, Yan, Ye, Yuanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513187/
https://www.ncbi.nlm.nih.gov/pubmed/34645519
http://dx.doi.org/10.1186/s13578-021-00681-7