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Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA

BACKGROUND: The function and regulatory mechanism of FBXO43 in breast cancer (BC) are still unclear. Here, we intended to determine the role and mechanism of FBXO43 in BC. METHODS: FBXO43 expression in BC was evaluated by analysis of The Cancer Genome Atlas (TCGA). RT-qPCR and western blotting were...

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Detalles Bibliográficos
Autores principales: Ma, Rulan, Zhu, Kun, Yuan, Dawei, Gong, Meijun, Li, Yijun, Li, Kang, Meng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513237/
https://www.ncbi.nlm.nih.gov/pubmed/34645483
http://dx.doi.org/10.1186/s12967-021-03100-0