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Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA
BACKGROUND: The function and regulatory mechanism of FBXO43 in breast cancer (BC) are still unclear. Here, we intended to determine the role and mechanism of FBXO43 in BC. METHODS: FBXO43 expression in BC was evaluated by analysis of The Cancer Genome Atlas (TCGA). RT-qPCR and western blotting were...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513237/ https://www.ncbi.nlm.nih.gov/pubmed/34645483 http://dx.doi.org/10.1186/s12967-021-03100-0 |