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Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding

AIM: Growth hormone secretagogue receptor 1a (GHS-R1a) is widely distributed in brain including the hippocampus. Studies have demonstrated the critical role of hippocampal ghrelin/GHS-R1a signaling in synaptic physiology, memory and cognitive dysfunction associated with Alzheimer’s disease (AD). How...

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Detalles Bibliográficos
Autores principales: Li, Nan, Li, Na, Xu, Fenghua, Yu, Ming, Qiao, Zichen, Zhou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513281/
https://www.ncbi.nlm.nih.gov/pubmed/34641940
http://dx.doi.org/10.1186/s13041-021-00866-8