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FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway

BACKGROUND: Breast cancer (BC) is one of the most common cancers and the leading cause of death in women. Previous studies have demonstrated that FAM49B is implicated in several tumor progression, however, the role and mechanism of FAM49B in BC remain to be explored. Therefore, in this study, we aim...

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Detalles Bibliográficos
Autores principales: Li, Yanhui, Xiong, Yue, Wang, Zhen, Han, Jianjun, Shi, Sufang, He, Jinglan, Shen, Na, Wu, Wenjuan, Wang, Rui, Lv, Weiwei, Deng, Yajun, Liu, Weiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513284/
https://www.ncbi.nlm.nih.gov/pubmed/34645466
http://dx.doi.org/10.1186/s12935-021-02244-9