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An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development

BACKGROUND: SETD1A, a member of SET1/MLL family H3K4 methyltransferases, is involved in the tumorigenesis of numerous cancers. However, the biological role and mechanism of SETD1A in non-small cell lung cancer (NSCLC) remain to be elucidated. METHODS: The expression of SETD1A, NEAT1, EZH2, and β-cat...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Liu, Jian, Li, Kai, Yang, Ganghua, Chen, Sisi, Wu, Jie, Xie, Xinming, Ren, Hong, Pang, Yamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513302/
https://www.ncbi.nlm.nih.gov/pubmed/34645486
http://dx.doi.org/10.1186/s13046-021-02119-x