Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice

BACKGROUND: Individuals with Fragile X syndrome (FXS) and autism spectrum disorder (ASD) exhibit an array of symptoms, including sociability deficits, increased anxiety, hyperactivity, and sensory hyperexcitability. It is unclear how endocannabinoid (eCB) modulation can be targeted to alleviate neur...

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Detalles Bibliográficos
Autores principales: Pirbhoy, Patricia S., Jonak, Carrie R., Syed, Rashid, Argueta, Donovan A., Perez, Pedro A., Wiley, Mark B., Hessamian, Keon, Lovelace, Jonathan W., Razak, Khaleel A., DiPatrizio, Nicholas V., Ethell, Iryna M., Binder, Devin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513313/
https://www.ncbi.nlm.nih.gov/pubmed/34645383
http://dx.doi.org/10.1186/s11689-021-09394-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513313/
https://www.ncbi.nlm.nih.gov/pubmed/34645383
http://dx.doi.org/10.1186/s11689-021-09394-x

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